Main city: Greenville
Timezone: Central
Phone type: Landline
Operator: Windstream Missouri

Greenville, a small city located on U.S. Highway 67 near the intersection with Route D and E in Wayne County, Missouri in the United States along the St. Francis River. The population was 511 at the 2010 census. Greenville was incorporated and founded as the county seat of Wayne County in 1819. ^source

Area code 573 serves most of the eastern half of Missouri outside the immediate St. Louis area. It extends across nearly the entire width of the state, with the state's northeast corner as the northeastern tip, the Lake of the Ozarks at the western tip and Doniphan as the southwestern tip. It also serves all of southeastern Missouri (including the Missouri Bootheel area) and areas adjacent to the Mississippi River. It was created on January 7, 1996 as a split from area code 314. ^source